Beyond the Symptoms | An Expert Interview Series by LUF | Live UTI Free
Beyond the Symptoms is an interview series by Live UTI Free (LUF) that explores the science, solutions, and stories behind pelvic health, UTIs, and chronic urinary infections.
Host Melissa Kramer engages in deep conversations with leading medical experts, researchers, and healthcare innovators who share breakthrough insights beyond conventional diagnoses and treatments.
Each episode uncovers cutting-edge research on biofilms, embedded infections, antibiotic resistance, and innovative diagnostic approaches while examining how these conditions impact quality of life. Whether you're a patient navigating recurrent UTIs, interstitial cystitis, or chronic pelvic pain, a healthcare practitioner seeking evidence-based approaches, or a curious mind interested in women's health advocacy, this podcast provides actionable information about complex pelvic health conditions.
Episodes feature world-renowned urologists, urogynecologists, researchers, and patient advocates sharing clinical insights and practical strategies.
Explore our comprehensive resources at liveutifree.com, find additional studies at linktr.ee/liveutifree, watch video interviews on YouTube (@LiveUTIFree), and join our supportive community on Instagram (@liveutifree).
Beyond the Symptoms | An Expert Interview Series by LUF | Live UTI Free
Why UTI Tests Keep Failing You And What Science Is Doing About It | Prof. Jenny Roan with Live UTI Free
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If you’ve ever been told your urine test came back negative but you know something is wrong, this episode is for you.
Host Melissa Kramer speaks with Professor Jenny Roan, Head of the Centre for Urological Biology at University College London (UCL), to get into the science that most people living with recurrent or chronic UTI desperately want to understand. From why the dipstick test misses so many real infections, to what’s actually happening inside the bladder wall when antibiotics stop working, Professor Roan breaks it all down in plain language, without dismissal.
Professor Roan also shares details of a novel treatment her team at UCL has developed, CapFuran, a microencapsulated nitrofurantoin designed to deliver the antibiotic directly into the bladder wall to target embedded bacteria and biofilms that standard antibiotics simply can’t reach. With a potential clinical trial horizon of 2026–2027, this is the research the chronic UTI community has been waiting for.
3 Key Takeaways
- Your negative test result doesn’t necessarily mean there’s no infection. Dilution, the wrong type of bacteria, mixed growth being discarded… There are multiple scientific reasons a real UTI can be missed. The research highlighting these inadequacies has existed for decades.
- Chronic UTI may involve bacteria that are literally hiding inside your bladder wall. These intracellular bacteria and biofilms are dormant and largely unreachable by standard short-course antibiotics, which is why a three-day course of nitrofurantoin often isn’t enough.
- Research into new treatments is moving forward and the patient community is part of the push. From the uro-immune vaccine to a novel encapsulated antibiotic therapy targeting embedded infection, there are promising options in development. The more patients ask questions and advocate for themselves, the harder it becomes to ignore this area of health.
Resources and Links
- Learn more and access related articles: liveutifree.com
- Subscribe to the LUF YouTube channel for video format
- Connect with Professor Jenny Roan via UCL or LinkedIn
